Gene Synthesis & DNA Synthesis Services
Gene Synthesis and DNA Synthesis services enable you to custom-clone your codon-optimized genes into your desired vector for optimal protein expression, regardless of length or complexity. Our expanded offering includes a wide range of synthetic DNA solutions, including gene fragment synthesis, synthetic DNA libraries, oligo synthesis, and CRISPR synthetic solutions. With a rapid turnaround time and cost-effective pricing, GENEWIZ provides complete gene synthesis solutions with the quality, speed, and support you need to achieve success in your research.
GENEWIZ Synthesis Services
Antibody Production and Viral Vector Products
DNA Synthesis Applications
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Protein Engineering
Boost protein expression levels for directed evolution and rational design with codon-optimized genes.
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Gene Therapy
Efficiently clone synthetic therapeutic genes into custom viral vectors to optimize expression and specificity of gene delivery.
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Vaccine Development
Encode safer molecular adjuvants via cutting-edge vaccine design with codon-optimized synthetic DNA.
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Genetic Engineering
Use synthetic genomes to generate novel biological functions and systems with CRISPR and other gene editing technologies.
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Antibody Discovery
Expedite candidate identification and screening for targeted therapeutic antibody engineering through codon-optimized gene constructs and libraries.
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Structural Biology
Use codon-optimized genes to rapidly express recombinant protein for structure determination in gene-to-protein pipelines.
Technical Resources
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Tech Note | High-Fidelity Production of In Vitro Transcription Plasmids with Long Poly(A) Sequences
Poly(A) tail sequences can impact the integrity of your mRNA plasmids for in vitro transcription. While longer poly(A) tails have been shown to increase their stability, tails greater than 100 bases are susceptible to truncations. Learn how the GENEWIZ proprietary mRNA plasmid preparation protocol can help you generate higher yields and preserve poly(A) tails of greater lengths compared to standard protocols for high-fidelity templates in our tech note.
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Tech Note | mRNA Production via Integrated Gene Synthesis and In Vitro Transcription
In vitro transcription (IVT) is a powerful technique to generate messenger RNA (mRNA) for a wide array of research and therapeutic applications. Transfection of mRNA enables very high protein expression, comparable to viral systems, with rapid onset. Read our tech note to learn how IVT, coupled with gene synthesis, can be used to synthesize mRNA of virtually any sequence quickly and efficiently.