Recombinant Antibody Production
Recombinant antibody production service combines gene synthesis with codon optimization for expression and purification of desired antibodies in as fast as 8 business days. The applications for recombinant antibodies (rAbs) are varied across biomedical and toxicological research. Monoclonal antibodies produced recombinantly are often used as biochemical markers, detection tools, or for developing effective therapeutic treatments that target cancer, autoimmune disorders, and a broad range of other diseases.
GENEWIZ equips researchers with a range of flexible and tailored solutions that save valuable time and accelerate innovation.
Antibody Expression in 8 Business Days
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1. Construct Design
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2. DNA Synthesis
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3. Cloning and Plasmid Prep
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4. Transient Transfection
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5. Antibody Purification and QC
Customize Your Antibody Synthesis Analysis
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Choose your antibody type: IgG, Bispecific, ScFv, VHH, Fab, Fc Fusion
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Use in-house optimized vector or submit your own vector backbone for free
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Multiple expression platforms available: CHO, HEK293
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Small to large-scale expression volumes: Small-scale: 3ml to 30ml, Medium-scale: 100ml to 500 ml, Large-scale: 1 L to 20 L
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Multiple purification strategies: Protein A, Protein G, Protein L, Ni-NTA, SEC
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Standard QC includes protein concentration by A280, purity test and report by SDS PAGE, endotoxin testing, plus aggregation testing add-on available
Advantages of Recombinant Antibodies
In recombinant antibody production, monoclonal antibodies are produced artificially through genetic engineering and other related techniques. Genetically engineered antibodies are specifically valuable in scientific research due to their ability to recognize individual antigenic sites on almost any molecule including drugs, hormones, microbial antigens, and cell receptors. Recombinant antibodies that react with cancer antigens, for example, can be used to identify cancer cells in tissue samples and ultimately fuel the the development of cancer-fighting drugs and therapies.
- Increase reproducibility, control and consistency
- Faster production time over hybridoma technology
- Easier to switch antibodies into a preferable format
- Animal-free process
For more frequently asked questions (FAQs) please visit our antibody FAQ page.
Features and Benefits
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Reliable Provider: >95% on- time delivery
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Rapid Turnaround: Industry-leading turnaround time starting from 8 business days, including DNA synthesis to purified antibody
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Stringent QC: Multiple QC checkpoints, including protein concentration, aggregation, and purity
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Technical Support: Ph.D. scientists available for consultation and support at every step
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Flexibility: High-throughput antibody production and purification
Technical Resources
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Application Note | Accelerating Recombinant Antibody Production
Recombinant antibody production is a cornerstone of modern biotechnology and research, but it faces the significant challenge of achieving high yields. In this application note, discover how to enhance expression efficiency while reducing production times with an optimized vector backbone workflow.