An Efficient and High-Fidelity Approach to AAV Plasmid Preparation (Tech Note)

Preserving the integrity of inverted terminal repeat (ITR) sequences in adeno-associated virus (AAV) plasmids is important to produce recombinant AAV (rAAV) vectors. Azenta’s proprietary AAV plasmid preparation service delivers superior quality for midi to giga-scale AAV vectors, while maintaining the integrity of ITR regions. Our new process includes pre- and post-preparation quality controlled (QC) steps that leverage Azenta's AAV-ITR Sanger sequencing capabilities for full sequence verification and ensures delivery of intact ITR clones for your research.

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AAV ITR Sequencing Case Study

AAV ITR Sequencing Tech Note

Azenta has developed a high-quality, direct Sanger sequencing method that reads through both intact and commonly mutated inverted terminal repeat (ITR) regions of adeno-associated virus (AAV). This method is an effective tool for assessing the integrity of ITRs in AAV plasmids.

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Single Cell Case Study

Add More Life to Your Data: Optimizing Single-Cell RNA-Seq with Dead Cell Removal (Tech Note)

This tech note describes how Azenta scientists used optimized single-cell workflows, including dead cell removal, to overcome low viability and generate high-quality sequencing data on the 10x Genomics® Chromium™ platform.

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Single Cell Case Study

Uncovering Cell Type-Specific Expression Profiles in the Tumor Microenvironment with Ultra-Low Input RNA-Seq (Case Study)

Using only ~50 tumor cells as input, Azenta generated high quality transcriptomic data that enabled researchers to publish in a top journal.

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Single Cell Case Study

Single-Cell RNA-Seq Analysis Identifies Rare Drug - Resistant Cancer Stem Cells (Case Study)

Discover the value of scRNA-seq in identifying rare cells, characterizing their transcriptomes, and discovering potential biomarkers in this Azenta-exclusive study.

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genoTYPER-NEXT Case Study

Rapid, Scalable, and Ultra-Sensitive Validation of Allele-Specific Gene Editing Events with genoTYPER-NEXTTM (Case Study)

Discover the powerful capability of genoTYPER-NEXT in this illuminating case study that discusses this new technology and how it's helping researchers analyze NGS DATA.

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Synthetic Libraries Tech Note

Trimer-Controlled Synthetic Libraries (Case Study)

Download this case study now to learn why researchers at a large bio-pharmaceutical company chose Azenta’s Trimer-Controlled Library solution to obtain a highly accurate mutant library.

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Synthetic Libraries Tech Note

Competent Cell Selection Guide

This guide will help you choose protocols for making competent cells and appropriate strains for your experiment.

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Multiplexing microbes on the PacBio Sequel: Feasibility, benefits, and recent developments (Tech Note)

This study proves the feasibility of multiplexing and highlights the key advantages of the PacBio Sequel platform as compared to its predecessor, the RSII.

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Detection of Previously Unidentified Structural Variants Involved in Glioblastoma Using PacBio SequelTM Sequencing

This case study looks at how Azenta utilized the PacBio® Sequel™ long-read technology to help a customer improve detection of structural variants within glioblastoma samples.

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