Whole Genome Sequencing with the PacBio Sequel utilizes Single Molecule, Real-Time (SMRT) technology that combines long read technology and rapid sequencing to produce the highest-quality de novo assemblies, phase alleles and variants, and significantly improve the detection of large structural variants. The new PacBio Sequel system uses SMRT cells containing 1 million Zero-Mode Waveguides to generate 7x the output of the PacBio RSII with up to 99.999% accuracy.
Download the Tech Note: Multiplexing Microbes on the PacBio Sequel: Feasibility, Benefits, and Recent Developments
Whereas short read technologies are limited in their ability to identify Indels, a single PacBio read can discover a wide range of variants, from SNPs and small Indels to large insertions and deletions. Assembled, PacBio reads even allow for identification of large structural rearrangements and phasing of variants, even in highly repetitive sequences.
GENEWIZ is a certified service provider for Illumina and Life Technology NGS platforms. For information on our NGS platforms as well as recommended configurations for your projects, please visit the NGS Platforms page. GENEWIZ does not guarantee data output or quality for sequencing only projects.