*Development of assays for other cancer types with flexibility to add or subtract genes from premade panels available upon request.
Discovery Cancer Panels
Amplicon Cancer Panel
Cancer Hotspot Panel
|Sequencing Platform||Illumina MiSeq or HiSeq||Illumina MiSeq||Ion PGM®|
|Cancer Types Assayed||19 distinct gene panels, each assays a specific cancer (organ) type||Single gene panel assays multiple cancer types||Single gene panel assays multiple cancer types|
|Genes Covered||≈150 - 400||48||50|
|Genomic Variation Detection||
|Target Regions||≈ 2 - 5.4 Mb, consisting of all exons, UTRs, and relevant intron regions||≈35 Kb, consisting of mutational hot spots||≈ 39 Kb, consisting of mutational hot spots|
|Average Depth||> 100x*||> 100x*||> 100x*|
|Target Enrichment||Agilent SureSelect Targeted Enrichment||Illumina Targeted Amplicon Sequencing||Life Technologies Targeted Amplicon Sequencing|
|DNA Input||> 100 ng||> 250 ng||> 10 ng|
GENEWIZ accepts formalin-fixed, paraffin-embedded (FFPE) thin sections (slides), purified genomic DNA, or fresh, frozen samples for Cancer Panel projects. For detailed sample submission requirements please visit our Sample Submission Guidelines page.
All customers receive their raw data as FASTQ files. Mutation discovery and customizable data analysis packages are available by request.
GENEWIZ is a certified service provider for Illumina NGS platforms and the PacBio Sequel. Please visit our NGS Platforms page for more information.