Immuno-Profiling for bulk repertoire analysis |
Single-Cell Immuno-Profiling for physical pairing of chains |
|
BCR sequencing (VH and VL chains) | Yes | Yes |
TCR Sequencing (α and β chains) |
Yes | Yes |
Starting materials* | Total RNA Blood Cell pellet Tissue |
Cell suspension |
V(D)J amplification method | Proprietary 5' RACE | Targeted enrichment of cDNA with cell-specified barcodes |
Physical pairing of VH/VL or α/β chains | No | Yes |
*Visit our Sample Submissions Guidelines for more details.
In this webinar, we review how recent advancements of the 10x Genomics Chromium™ system, coupled with GENEWIZ developmental efforts, can benefit the researcher. In addition, we spotlight the new Single-Cell V(D)J Solution, which can be used in conjunction with single-cell transcriptome profiling to identify pairing of full-length BCR and TCR sequences.
Interactive HTML reports include the following:
The LoupeTM Cell Browser from 10x Genomics provides interactive tools including the following: