WHOLE GENOME SEQUENCING

Receive the comprehensive genome analysis you need for your research project. Whole genome sequencing (WGS) provides unprecedented access to genomic information — expediting breakthroughs in healthcare, oncology, biomarker discovery, agriculture, and metagenomics.

Azenta Life Sciences, formerly GENEWIZ's expertise in the latest technologies and bioinformatics enable us to deliver high-quality data and analysis for the genomes of all organisms including humans, animals, plants, bacteria, and viruses.

Whole Genome Sequencing Services

Short-Read Human WGS

Analyze human genomes with speed and accuracy using the Illumina® NovaSeq™ or HiSeq®. CLIA-compliant whole genome sequencing is available for clinical researchers.

Short-Read Non-Human WGS

Perform de novo assembly and variant detection on the Illumina® MiSeq®, HiSeq®, or NovaSeq™ with optimal throughput and low cost per base. Extraction through data analysis is available.

Long-Read Whole Genome Sequencing

Long-read sequencing on the PacBio® Sequel® delivers up to 60 kb reads with contig N50 > 1 Mb. Generate reference quality assemblies for prokaryotic genomes. Ideal for structural variant calling in eukaryotes.

Low-Pass Whole Genome Sequencing

Accurately detect genetic variation throughout genomes of a multitude of species. Achieve up to 99% accuracy of variant call detection at a very low sequence coverage (0.1X<10X) using imputation algorithms.

Find the right NGS solution for your project using our interactive guide.

WGS Coverage For Any Application

Features & Benefits

Superior Data Quality

Exceeding manufacturer’s benchmarks
Fast Turnaround

Starting at 1 week for sequencing
European Provider

Sequencing available at our lab in Leipzig, Germany

Dedicated Ph.D.-level support at every step with real-time project
updates through our online system

Flexible data amounts starting at 10M read pairs

Latest platforms - Illumina NovaSeq delivers the highest throughput on the market

Highly scalable - submit one sample or as many as hundreds

Technical Resources

Workbook | Exploring Bioinformatics for Genome and Transcriptome Sequencing Data

For those new to bioinformatics, analyzing massive amounts of NGS data can be a daunting task. Download Azenta’s bioinformatics workbook to learn how to analyze whole genome sequencing (WGS) and RNA sequencing (RNA-Seq) data with bioinformatics tools to reveal biological insights for your research.

Case Study | Detection of Previously Unidentified Structural Variants Involved in Glioblastoma Using PacBio^® Sequel^® Sequencing

This case study looks at how Azenta utilized the PacBio Sequel long-read technology to help a customer improve detection of structural variants within glioblastoma samples.

Webinar | A New Paradigm in DNA Sequencing – Highly Accurate Single-Molecule Long Reads (Hosted by PacBio)

In this PacBio-hosted webinar, Jonas Korlach, PacBio Chief Scientific Officer, and Dave Corney, Azenta Associate Principal Scientist, Next Generation Sequencing, describe the recent release of Sequel System 6.0, which has revolutionized long-read sequencing by providing users the ability to generate highly accurate single-molecule reads.

Tech Note | Multiplexing Microbes on the PacBio Sequel: Feasibility, Benefits, and Recent Developments

This study proves the feasibility of multiplexing and highlights the key advantages of the PacBio Sequel platform as compared to its predecessor, the RSII.

Best Practices | Preparation of High Molecular Weight DNA

High-quality high molecular weight (HMW) genomic DNA (≥50 kb) is critical to achieving long read lengths on platforms such as the 10x Genomics^® Chromium™ and the PacBio Sequel. Follow these guidelines to generate the best possible WGS results.

The $100 Genome: Using Low-Pass Whole Genome Sequencing as an Alternative to Genotyping Arrays

In this webinar originally presented at the ASHG 2020 Virtual Meeting, learn how low-pass WGS overcomes the inherent limitations and biases of traditional arrays, offering an inexpensive, high-throughput alternative for detecting genome-wide genetic variation and novel variants.

Workshop & Roundtable Discussion | Exploring Bioinformatics for Whole Genome Sequencing (WGS) Data

In this recording of our WGS bioinformatics workshop & roundtable discussion led by bioinformatics scientist Zain Alvi, Ph.D., we'll guide you through the WGS bioinformatics process to help you learn to interpret WGS bioinformatics results, as well as address common challenges and answer frequently asked questions (FAQs).

WHOLE GENOME SEQUENCING