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ChIP-Seq (chromatin immunoprecipitation sequencing) combines the highly effective chromatin immunoprecipitation (ChIP) methodology and next generation sequencing (NGS) to analyze protein-DNA interactions. These interactions are important for a vast quantity of biological processes involved in normal development and disease progression, such as gene regulation, checkpoint regulation, DNA repair, and DNA synthesis. ChIP-Seq is a valuable tool for discerning and quantifying the specific DNA sequences where proteins bind or epigenetic modifications exist.
Now accepting plant tissue!
Features & Benefits
Utilizes NGS technology to generate millions of reads across each sample, driving discovery
Offers higher resolution, cleaner data, and the superior ability to identify novel enrichment sites compared to ChIP-array technology
Comprehensive bioinformatics solutions
Selects any chromatin immunoprecipitated protein and modifications for analysis, including transcription factors, structural proteins, protein modifications, and DNA modifications
Low-input DNA requirement
Fast and cost-effective
ChIP-Seq Workflow
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Experimental Design
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Library Preparation
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Sequencing
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Data Analysis
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Sample Submission Guidelines
GENEWIZ accepts chromatin immunoprecipitated DNA (ChIP DNA) and plant tissue for ChIP-Seq projects. Please visit our Sample Submission Guidelines page for details.
Deliverables
NGS Platforms
Azenta is a certified service provider for Illumina and Life Technology NGS platforms. For information on our NGS platforms as well as recommended configurations for your projects, please visit the NGS Platforms page. Azenta does not guarantee data output or quality for sequencing only projects.
HOW TO ORDER
*Samples must arrive at the GENEWIZ New Jersey laboratory before 10:00 am EST to qualify for Same Day service. Note that direct-sequencing templates are not available for our Same Day service.
