GENEWIZ Featured Publications

DNA Sequencing Services

Alter SE, Munshi-South J, Stiassny MLJ. Genome-wide SNP data reveal cryptic phylogeographic structure and microallopatric divergence in a rapids-adapted clade of cichlids from the Congo River. Molecular Ecology. 2016. doi:10.1111/mec.13973.

Husseneder C, Park J-S, Howells A, Tikhe CV, Davis JA. Bacteria Associated With Piezodorus guildinii (Hemiptera: Pentatomidae), With Special Reference to Those Transmitted by Feeding. Environmental Entomology. 2016. doi:10.1093/ee/nvw112.

Orlova N, Gerding M, Ivashkiv O, et al. The replication initiator of the cholera pathogen's second chromosome shows structural similarity to plasmid initiators. Nucleic Acids Research. 2016. doi:10.1093/nar/gkw1288.

Kim S-K, Chung D, Himmel ME, Bomble YJ, Westpheling J. Engineering the N-terminal End of CelA results in improved performance and growth of Caldicellulosiruptor bescii on crystalline cellulose. Biotechnology and Bioengineering. 2016. doi:10.1002/bit.26242.

Moyerbrailean GA, Kalita CA, Harvey CT, Wen X, Luca F, Pique-Regi R. Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding? PLOS Genetics. 2016;12(2). doi:10.1371/journal.pgen.1005875.

Nyborg AC, Ward C, Zacco A, et al. A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties. Plos One. 2016;11(12). doi:10.1371/journal.pone.0167935.

Tam K, Schultz M, Reyes-Robles T, et al. Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5. mBio. 2016;7(6). doi:10.1128/mbio.02024-16.

Chojnacka K, Bilinska B, Mruk DD. Annexin A2 is critical for blood-testis barrier integrity and spermatid disengagement in the mammalian testis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2017;1864(3):527-545. doi:10.1016/j.bbamcr.2016.12.012.

Englaender JA, Zhu Y, Shirke AN, et al. Expression and secretion of glycosylated heparin biosynthetic enzymes using Komagataella pastoris. Applied Microbiology and Biotechnology. 2016. doi:10.1007/s00253-016-8047-x.

Surel CCA, Guillet M, Lenoir M, et al. Remodeling of the Inner Hair Cell Microtubule Meshwork in a Mouse Model of Auditory Neuropathy AUNA1. eneuro. 2016;3(6). doi:10.1523/eneuro.0295-16.2016.

Liu X-Y, Gong X-Y, Zheng C, et al. Molecular epidemiological survey of bacterial and parasitic pathogens in hard ticks from eastern China. Acta Tropica. 2017;167:26-30. doi:10.1016/j.actatropica.2016.12.010.

Nogales A, Martinez-Sobrido L, Topham DJ, Dediego ML. NS1 protein amino acid changes D189N and V194I affect interferon responses, thermosensitivity and virulence of circulating H3N2 human influenza A viruses. Journal of Virology. 2016. doi:10.1128/jvi.01930-16.

Copin R, Wang X, Louie E, et al. Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity. PLOS Pathogens. 2016;12(12). doi:10.1371/journal.ppat.1006111.

Gardner TJ, Stein KR, Duty JA, et al. Functional screening for anti-CMV biologics identifies a broadly neutralizing epitope of an essential envelope protein. Nature Communications. 2016;7:13627. doi:10.1038/ncomms13627.

Wang Y, Chandler C. Candidate pathogenicity islands in the genome of ‘Candidatus Rickettsiella isopodorum’, an intracellular bacterium infecting terrestrial isopod crustaceans. PeerJ. 2016;4. doi:10.7717/peerj.2806.

Munck I, Luther T, Wyka S, et al. Soil and Stocking Effects on Caliciopsis Canker of Pinus strobus L. Forests. 2016;7(11):269. doi:10.3390/f7110269.

Whitaker WB, Jones JA, Bennett RK, et al. Engineering the biological conversion of methanol to specialty chemicals in Escherichia coli. Metabolic Engineering. 2016. doi:10.1016/j.ymben.2016.10.015.

Zhang Y-L, Li Z-F, Feng Z-L, et al. Functional Analysis of the Pathogenicity-Related Gene VdPR1 in the Vascular Wilt Fungus Verticillium dahliae. Plos One. 2016;11(11). doi:10.1371/journal.pone.0166000.

Merewitz E, Xu Y, Huang B. Differentially Expressed Genes Associated with Improved Drought Tolerance in Creeping Bentgrass Overexpressing a Gene for Cytokinin Biosynthesis. Plos One. 2016;11(11). doi:10.1371/journal.pone.0166676.

Cruz FSD, Diolaiti D, Turk AT, et al. A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma. Genome Medicine. 2016;8(1). doi:10.1186/s13073-016-0366-0.

Mouhamadou B, Sage L, Périgon S, et al. Molecular screening of xerophilic Aspergillus strains producing mycophenolic acid. Fungal Biology. 2016. doi:10.1016/j.funbio.2016.10.001.

Dam HT, Häggblom MM. Impact of estuarine gradients on reductive dechlorination of 1,2,3,4-tetrachlorodibenzo-p-dioxin in river sediment enrichment cultures. Chemosphere. 2017;168:1177-1185. doi:10.1016/j.chemosphere.2016.10.082.

Boyanapalli SS, Li W, Fuentes F, et al. Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells. Pharmacological Research. 2016;114:175-184. doi:10.1016/j.phrs.2016.10.021.

Tripler TN, Teschke CM, Alexandrescu AT. NMR assignments for the insertion domain of bacteriophage Sf6 coat protein. Biomolecular NMR Assignments. 2016. doi:10.1007/s12104-016-9716-5.

Gao X-Y, Li K, Jiang L-L, et al. Developmental toxicity of auranofin in zebrafish embryos. Journal of Applied Toxicology. 2016. doi:10.1002/jat.3410.

Sundar GS, Islam E, Gera K, Breton YL, Mciver KS. A PTS EII mutant library in Group A Streptococcus identifies a promiscuous man-family PTS transporter influencing SLS-mediated hemolysis. Molecular Microbiology. 2016. doi:10.1111/mmi.13573.

Ottomeyer M, Graham CD, Legg AD, et al. Prevalence of Nasal Colonization by Methicillin-Resistant Staphylococcus aureus in Persons Using a Homeless Shelter in Kansas City. Frontiers in Public Health. 2016;4. doi:10.3389/fpubh.2016.00234.

Wang D-W, Lin H-Y, He B, et al. An Efficient One-Pot Synthesis of 2-(Aryloxyacetyl)cyclohexane-1,3-diones as Herbicidal 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. Journal of Agricultural and Food Chemistry. 2016;64(47):8986-8993. doi:10.1021/acs.jafc.6b04110.

Qiu Y, Hassaninasab A, Han G-S, Carman GM. Phosphorylation of Dgk1 Diacylglycerol Kinase by Casein Kinase II Regulates Phosphatidic Acid Production in Saccharomyces cerevisiae. Journal of Biological Chemistry. October 2016. doi:10.1074/jbc.m116.763839.

Gao L, Ren W, Zhang L, et al. PTENp1, a natural sponge of miR-21, mediates PTEN expression to inhibit the proliferation of oral squamous cell carcinoma. Molecular Carcinogenesis. 2016. doi:10.1002/mc.22594.

Fu J, Zhang X, Chen P, Zhang Y. Endoplasmic reticulum stress is involved in 2,4-dichlorophenol-induced hepatotoxicity. The Journal of Toxicological Sciences. 2016;41(6):745-756. doi:10.2131/jts.41.745.

Cheng Y, Gu J, Xue H, et al. Identification of Four SNPs in LHB Gene and Their Associations with Sperm Qualities of Chinese Buffaloes. Animal Biotechnology. 2016:1-6. doi:10.1080/10495398.2016.1244068.

Kendra JA, Fuente CDL, Brahms A, et al. Ablation of programmed -1 ribosomal frameshifting in Venezuelan equine encephalitis virus results in attenuated neuropathogenicity. Journal of Virology. 2016. doi:10.1128/jvi.01766-16.

Eick GN, Bridgham JT, Anderson DP, Harms MJ, Thornton JW. Robustness of reconstructed ancestral protein functions to statistical uncertainty. Molecular Biology and Evolution. 2016. doi:10.1093/molbev/msw223.

Chhum P, Yu H, An B, Doyon BR, Lin Y-S, Brodsky B. Consequences of Glycine Mutations in the Fibronectin Binding Sequence of Collagen. Journal of Biological Chemistry. 2016. doi:10.1074/jbc.m116.753566.

Hawkins TD, Hagemeyer JCG, Warner ME. Temperature moderates the infectiousness of two conspecific Symbiodinium strains isolated from the same host population. Environmental Microbiology. 2016. doi:10.1111/1462-2920.13535.

Liu X, Edinger R, Klemens C, et al. A MicroRNA Cluster miR-23∼24∼27 Is Upregulated by Aldosterone in the Distal Kidney Nephron where It Alters Sodium Transport. Journal of Cellular Physiology. 2016. doi:10.1002/jcp.25599.

Schneeberger VE, Allaj V, Gardner EE, Poirier JT, Rudin CM. Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis. Plos One. 2016;11(9). doi:10.1371/journal.pone.0160587.

Thomas JA, Quintana ADB, Bosch MA, et al. Identification of Essential Genes in the Salmonella Phage SPN3US Reveals Novel Insights into Giant Phage Head Structure and Assembly. Journal of Virology. 2016;90(22):10284-10298. doi:10.1128/jvi.01492-16.

Munck IA, Wyka SA, Bohne MJ, Green WJ, Siegert NW. First Report of Diplodia corticola Causing Bleeding Cankers on Black Oak (Quercus velutina). Plant Disease. 2016. doi:10.1094/pdis-08-16-1118-pdn.

Qin T, Bi R, Fan W, Kang H, Ma P, Gu B. Novel mutations in quinolone resistance-determining regions of gyrA, gyrB, parC and parE in Shigella flexneri clinical isolates from eastern Chinese populations between 2001 and 2011. European Journal of Clinical Microbiology & Infectious Diseases. December 2016. doi:10.1007/s10096-016-2761-2.

Bialk P, Sansbury B, Rivera-Torres N, Bloh K, Man D, Kmiec EB. Analyses of point mutation repair and allelic heterogeneity generated by CRISPR/Cas9 and single-stranded DNA oligonucleotides. Scientific Reports. 2016;6:32681. doi:10.1038/srep32681.

Mashruwala AA, Bhatt S, Poudel S, Boyd ES, Boyd JM. The DUF59 Containing Protein SufT Is Involved in the Maturation of Iron-Sulfur (FeS) Proteins during Conditions of High FeS Cofactor Demand in Staphylococcus aureus. PLoS Genet PLOS Genetics. 2016;12(8). doi:10.1371/journal.pgen.1006233.

Paulraj A, Musthafa MS, Altaff K, et al. Chytrid Batrachochytrium dendrobatidis fungal infection in freshwater prawn, Macrobrachium rosenbergii (de Man) - A new report. Aquaculture. 2016;464:521-528. doi:10.1016/j.aquaculture.2016.07.035.

Edgington HA, Ingram CM, Taylor DR. Cyto-nuclear discordance suggests complex evolutionary history in the cave-dwelling salamander,Eurycea lucifuga. Ecology and Evolution. 2016;6(17):6121-6138. doi:10.1002/ece3.2212.

Yeh I, Tee MK, Botton T, et al. NTRK3 kinase fusions in Spitz tumours. J Pathol The Journal of Pathology. 2016. doi:10.1002/path.4775.

Coldren GA, Barreto C, Wykoff D, et al. Chronic warming stimulates growth of marsh grasses more than mangroves in a coastal wetland ecotone. Ecology. 2016. doi:10.1002/ecy.1539.

Liu P, Jia M-Z, Zhou XE, et al. The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer. Acta Pharmacologica Sinica Acta Pharmacol Sin. 2016;37(9):1259-1272. doi:10.1038/aps.2016.69.

Kaminski R, Chen Y, Salkind J, et al. Negative Feedback Regulation of HIV-1 by Gene Editing Strategy. Sci Rep Scientific Reports. 2016;6:31527. doi:10.1038/srep31527.

Kamath PL, Sepulveda AJ, Layhee M. Genetic reconstruction of a bullfrog invasion to elucidate vectors of introduction and secondary spread. Ecol Evol Ecology and Evolution. 2016;6(15):5221-5233. doi:10.1002/ece3.2278.

Poultney CS, Goldberg AP, Drapeau E, et al. Identification of Small Exonic CNV from Whole-Exome Sequence Data and Application to Autism Spectrum Disorder. The American Journal of Human Genetics. 2013;93(4):607-619. doi:10.1016/j.ajhg.2013.09.001.

Ma C, Zhang J, Wang J. Pharmacological Characterization of the Spectrum of Antiviral Activity and Genetic Barrier to Drug Resistance of M2-S31N Channel Blockers. Molecular Pharmacology. 2016;90(3):188-198. doi:10.1124/mol.116.105346.

Dowell F, Cardman Z, Dasarathy S, et al. Microbial Communities in Methane- and Short Chain Alkane-Rich Hydrothermal Sediments of Guaymas Basin. Front Microbiol Frontiers in Microbiology. 2016;7. doi:10.3389/fmicb.2016.00017.

Wernick DG, Pontrelli SP, Pollock AW, Liao JC. Sustainable biorefining in wastewater by engineered extreme alkaliphile Bacillus marmarensis. Sci Rep Scientific Reports. 2016;6:20224. doi:10.1038/srep20224.

Jiang J, Zhang L, Zhou X, et al. Induction of site-specific chromosomal translocations in embryonic stem cells by CRISPR/Cas9. Sci Rep Scientific Reports. 2016;6:21918. doi:10.1038/srep21918.

Spielmann M, Kakar N, Tayebi N, et al. Exome sequencing and CRISPR/Cas genome editing identify mutations ofZAKas a cause of limb defects in humans and mice. Genome Research Genome Res. 2016;26(2):183-191. doi:10.1101/gr.199430.115.

Rodriguez NM, Wong WS, Liu L, Dewar R, Klapperich CM. A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples. Lab Chip. 2016;16(4):753-763. doi:10.1039/c5lc01392e.

Kim MK, Ingremeau F, Zhao A, Bassler BL, Stone HA. Local and global consequences of flow on bacterial quorum sensing. Nat Microbiol Nature Microbiology. 2016;1(1):15005. doi:10.1038/nmicrobiol.2015.5.

Fu S-F, He S, Shi X-S, Katukuri NR, Dai M, Guo R-B. The chemical properties and microbial community characterization of the thermophilic microaerobic pretreatment process. Bioresource Technology. 2015;198:497-502. doi:10.1016/j.biortech.2015.09.029.

Gene Synthesis Services

Zhang X, Wu H, Huang B, Li Z, Ye Q. One-pot synthesis of glutathione by a two-enzyme cascade using a thermophilic ATP regeneration system. Journal of Biotechnology. 2017;241:163-169. doi:10.1016/j.jbiotec.2016.11.034.

Guo D, Liu H, Gao G, et al. Creating a patient carried Men1 gene point mutation on wild type iPSCs locus mediated by CRISPR/Cas9 and ssODN. Stem Cell Research. 2017;18:67-69. doi:10.1016/j.scr.2016.12.007.

Song W, Li J, Liang Q, Marchisio MA. Can terminators be used as insulators into yeast synthetic gene circuits? Journal of Biological Engineering. 2016;10(1). doi:10.1186/s13036-016-0040-5.

Neely AE, Mandigo KA, Robinson RL, Ness TL, Weiland MH. Chimeric approach for narrowing a membrane-inserting region within human perforin. Protein Engineering Design and Selection. 2016. doi:10.1093/protein/gzw069.

Liu D, Tseng M, Epstein LF, et al. Evaluation of recombinant monoclonal antibody SVmab1 binding to NaV1.7 target sequences and block of human NaV1.7 currents. F1000Research. 2016;5:2764. doi:10.12688/f1000research.9918.1.

Sun Y, Ma L, Han D, et al. In vitro reconstitution of the cyclosporine specific P450 hydroxylases using heterologous redox partner proteins. Journal of Industrial Microbiology & Biotechnology. 2016. doi:10.1007/s10295-016-1875-y.

Rühl P, Pöll U, Braun J, Klingl A, Kletzin A. A Sulfur Oxygenase from the Haloalkaliphilic Bacterium Thioalkalivibrio paradoxus with atypically low Reductase Activity. Journal of Bacteriology. May 2016. doi:10.1128/jb.00675-16.

Shen B, Pan Q, Yang Y, et al. miR-224 Affects Mammary Epithelial Cell Apoptosis and Triglyceride Production by Downregulating ACADM and ALDH2 Genes. DNA and Cell Biology. 2017;36(1):26-33. doi:10.1089/dna.2016.3540.

Perez EM, Foley J, Tison T, Silva R, Ogembo JG. Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice. Oncotarget. January 2016. doi:10.18632/oncotarget.13770.

Li K, Wu J-Q, Jiang L-L, et al. Developmental toxicity of 2,4-dichlorophenoxyacetic acid in zebrafish embryos. Chemosphere. 2017;171:40-48. doi:10.1016/j.chemosphere.2016.12.032.

Achiron A, Zilkha-Falb R, Mashiach R, Gurevich M. RAM-589.555 a new Polymerase-1 inhibitor as innovative targeted-treatment for multiple sclerosis. Journal of Neuroimmunology. 2017;302:41-48. doi:10.1016/j.jneuroim.2016.10.016.

Díaz-Sáez L, Pankov G, Hunter WN. Open and compressed conformations of Francisella tularensis ClpP. Proteins: Structure, Function, and Bioinformatics. 2016;85(1):188-194. doi:10.1002/prot.25197.

Li S, Ding W, Zhang X, Jiang H, Bi C. Development of a modularized two-step (M2S) chromosome integration technique for integration of multiple transcription units in Saccharomyces cerevisiae. Biotechnology for Biofuels. 2016;9(1). doi:10.1186/s13068-016-0645-4.

Langlois CR, Pei F, Sindi SS, Serio TR. Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo. PLOS Genetics. 2016;12(11). doi:10.1371/journal.pgen.1006417.

Xu R, Qin R, Li H, et al. Generation of targeted mutant rice using a CRISPR-Cpf1 system. Plant Biotechnology Journal. 2016. doi:10.1111/pbi.12669.

Xie H, Hu J, Xiao C, Dai Y, Ding X, Xu Y. Exploration of ZEA cytotoxicity to mouse endometrial stromal cells and RNA-seq analysis. Journal of Biochemical and Molecular Toxicology. 2016. doi:10.1002/jbt.21874.

Qiang J, Tao Y-F, He J, Xu P, Bao J-W, Sun Y-L. miR-122 promotes hepatic antioxidant defense of genetically improved farmed tilapia (GIFT, Oreochromis niloticus) exposed to cadmium by directly targeting a metallothionein gene. Aquatic Toxicology. 2017;182:39-48. doi:10.1016/j.aquatox.2016.11.009.

Ma R, Han Z, Hu Z, et al. Structural basis for specific self-incompatibility response in Brassica. Cell Research. 2016;26(12):1320-1329. doi:10.1038/cr.2016.129.

Shih Y-E, Lin Y-C, Chung T-Y, et al. In vitro assay to estimate tea astringency via observing flotation of artificial oil bodies sheltered by caleosin fused with histatin 3. Journal of Food and Drug Analysis. 2016. doi:10.1016/j.jfda.2016.08.008.

Chen J, Gao S, Wang C, et al. Pathologically decreased expression of miR-193a contributes to metastasis by targeting WT1-E-cadherin axis in non-small cell lung cancers. Journal of Experimental & Clinical Cancer Research. 2016;35(1). doi:10.1186/s13046-016-0450-8.

Li S, Ding W, Zhang X, Jiang H, Bi C. Development of a modularized two-step (M2S) chromosome integration technique for integration of multiple transcription units in Saccharomyces cerevisiae. Biotechnology for Biofuels. 2016;9(1). doi:10.1186/s13068-016-0645-4.

Yin Y, Zhou XE, Hou L, et al. An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain. Cell Discovery. 2016;2:16042. doi:10.1038/celldisc.2016.42.

Martin JN, Ball LM, Solomon TL, Dewald AH, Criss AK, Columbus L. Neisserial Opa Protein–CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis. Biochemistry. 2016;55(31):4286-4294. doi:10.1021/acs.biochem.6b00124.

Lan D, Qu M, Yang B, Wang Y. Enhancing production of lipase MAS1 from marine Streptomyces sp. strain in Pichia pastoris by chaperones co-expression. Electronic Journal of Biotechnology. 2016;22:62-67. doi:10.1016/j.ejbt.2016.06.003.

Fujii T, Tsunesumi S-I, Sagara H, et al. Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis. Sci Rep Scientific Reports. 2016;6:29157. doi:10.1038/srep29157.

Tian Y, Wang Y, Sheng Z, Li T, Li X. A colorimetric detection method of pesticide acetamiprid by fine-tuning aptamer length. Analytical Biochemistry. 2016;513:87-92. doi:10.1016/j.ab.2016.09.004.

Yang S, Gao Y, Zhang S, Zhang Q, Sun D. Identification of Genetic Associations and Functional Polymorphisms of SAA1 Gene Affecting Milk Production Traits in Dairy Cattle. Plos One. 2016;11(9). doi:10.1371/journal.pone.0162195.

Barkoulas M, Velazquez AMV, Peluffo AE, Félix M-A. Evolution of New cis-Regulatory Motifs Required for Cell-Specific Gene Expression in Caenorhabditis. PLoS Genet PLOS Genetics. 2016;12(9). doi:10.1371/journal.pgen.1006278.

Yang Y, Qin X, Zhang W, Li Y, Zhang Z. Rapid and specific detection of porcine parvovirus by isothermal recombinase polymerase amplification assays. Molecular and Cellular Probes. 2016;30(5):300-305. doi:10.1016/j.mcp.2016.08.011.

Wang Y-C, Chin K-H, Tu Z-L, et al. Nucleotide binding by the widespread high-affinity cyclic di-GMP receptor MshEN domain. Nature Communications. 2016;7:12481. doi:10.1038/ncomms12481.

Wen S, Zhang J, Zhou P, et al. The anti-tumour effect of a DNA vaccine carrying a fusion gene of humanVEGFR2andIL-12. Biotechnology & Biotechnological Equipment. May 2016:1-7. doi:10.1080/13102818.2016.1207488.

Ruan J, Duan Y, Li F, Wang Z. Enhanced synergistic anti-Lewis lung carcinoma effect of a DNA vaccine harboring a MUC1-VEGFR2 fusion gene used with GM-CSF as an adjuvant. Clin Exp Pharmacol Physiol Clinical and Experimental Pharmacology and Physiology. 2016. doi:10.1111/1440-1681.12654.

Chen X, Wang Y, Chen X, et al. Genetic variants in the regulatory region of SLC10A1 are not associated with the risk of hepatitis B virus infection and clearance. Infection, Genetics and Evolution. 2016;44:495-500. doi:10.1016/j.meegid.2016.07.043.

Wen S, Zhang J, Zhou P, et al. The anti-tumour effect of a DNA vaccine carrying a fusion gene of humanVEGFR2andIL-12. Biotechnology & Biotechnological Equipment. May 2016:1-7. doi:10.1080/13102818.2016.1207488.

Roncarati D, Pelliciari S, Doniselli N, et al. Metal-responsive promoter DNA compaction by the ferric uptake regulator. Nature Communications Nat Comms. 2016;7:12593. doi:10.1038/ncomms12593.

Haller F, Knopf J, Ackermann A, et al. Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern. J Pathol The Journal of Pathology. 2016;238(5):700-710. doi:10.1002/path.4701.

Gutschner T, Haemmerle M, Genovese G, Draetta GF, Chin L. Post-translational Regulation of Cas9 during G1 Enhances Homology-Directed Repair. Cell Reports. 2016;14(6):1555-1566. doi:10.1016/j.celrep.2016.01.019.

Wang PL, Liu B, Xia Y, Pan CF, Ma T, Chen YJ. Long non-coding RNA-Low Expression in Tumor inhibits the invasion and metastasis of esophageal squamous cell carcinoma by regulating p53 expression. Molecular Medicine Reports Mol Med Report. 2016. doi:10.3892/mmr.2016.4913.

Liu G, Weston CQ, Pham LK, et al. Epigenetic Segregation of Microbial Genomes from Complex Samples Using Restriction Endonucleases HpaII and McrB. PLOS ONE PLoS ONE. 2016;11(1). doi:10.1371/journal.pone.0146064.

Zhang R, Hisano S, Tani A, Kondo H, Kanematsu S, Suzuki N. A capsidless ssRNA virus hosted by an unrelated dsRNA virus. Nat Microbiol Nature Microbiology. 2016;1(1):15001. doi:10.1038/nmicrobiol.2015.1.

Frei JC, Nyakatura EK, Zak SE, et al. Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses. Sci Rep Scientific Reports. 2016;6:19193. doi:10.1038/srep19193.

Next Generation Sequencing Services

Chen, L. et al. A reinforcing HNF4–SMAD4 feed-forward module stabilizes enterocyte identity. Nature Genetics (2019). doi:10.1038/s41588-019-0384-0

Wheeler, M. A. et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell 176, 581–596.e18 (2019). doi:10.1016/j.cell.2018.12.012

Li, S. et al. Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Nature Communications 10, (2019). doi:10.1038/s41467-019-09634-8

Rayman, J. B., Hijazi, J., Li, X., Kedersha, N., Anderson, P. J. & Kandel, E. R. Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory. Cell Reports 26, 2970-2983 (2019). doi:10.1016/j.celrep.2019.02.048

Aho, E. R. et al. Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Reports 26, 2916-2928 (2019). doi:10.1016/j.celrep.2019.02.047

Dunphy, L. J., Yen, P. & Papin, J. A. Integrated Experimental and Computational Analyses Reveal Differential Metabolic Functionality in Antibiotic-Resistant Pseudomonas aeruginosa. Cell Systems 8, 3–14.e3 (2019). doi:10.1016/j.cels.2018.12.002

Cheung, S., Parrella, A., Rosenwaks, Z. & Palermo, G. D. Genetic and epigenetic profiling of the infertile male. PLOS ONE 14, e0214275 (2019). doi:10.1371/journal.pone.0214275

Onishi, M., Pecani, K., Jones, T., IV, Pringle, J. R. & Cross, F. R. F-actin homeostasis through transcriptional regulation and proteasome-mediated proteolysis. Proceedings of the National Academy of Sciences 115, E6487–E6496 (2018). doi:10.1073/pnas.1721935115

Endalur Gopinarayanan, V. & Nair, N. U. A semi-synthetic regulon enables rapid growth of yeast on xylose. Nature Communications 9, (2018). doi:10.1038/s41467-018-03645-7

Botta, D. et al. Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection. Nature Immunology 18, 1249–1260 (2017). doi:10.1038/ni.3837

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Molecular Genetics

Chandramohan V, Pegram CN, Piao H, et al. Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a phase I/II clinical trial. Applied Microbiology and Biotechnology. 2016. doi:10.1007/s00253-016-8063-x.

Poore EA, Slifka DK, Raué H-P, et al. Pre-clinical development of a hydrogen peroxide-inactivated West Nile virus vaccine. Vaccine. 2017;35(2):283-292. doi:10.1016/j.vaccine.2016.11.080.