ChIP-Seq

ChIP-Seq (chromatin immunoprecipitation sequencing) combines the highly effective chromatin immunoprecipitation (ChIP) methodology and next generation sequencing (NGS) to analyze protein-DNA interactions. These interactions are important for a vast quantity of biological processes involved in normal development and disease progression, such as gene regulation, checkpoint regulation, DNA repair, and DNA synthesis. ChIP-Seq is a valuable tool for discerning and quantifying the specific DNA sequences where proteins bind or epigenetic modifications exist.


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Features & Benefits


Utilizes NGS technology to generate millions of reads across each sample, driving discovery


Offers higher resolution, cleaner data, and the superior ability to identify novel enrichment sites compared to ChIP-array technology


Comprehensive bioinformatics solutions


Selects any chromatin immunoprecipitated protein and modifications for analysis, including transcription factors, structural proteins, protein modifications, and DNA modifications


Low-input DNA requirement


Fast and cost-effective

ChIP-Seq Workflow

Extensive Quality Control is Performed at the Conclusion of Each Step of the Process
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    Experimental Design


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    Library Preparation


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    Sequencing


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    Data Analysis


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Sample Submission Guidelines

GENEWIZ accepts chromatin immunoprecipitated DNA (ChIP DNA) only for ChIP-Seq projects, we do not perform the chromatin immunoprecipitation for you. Please visit our Sample Submission Guidelines page for specifications on submitting your ChIP DNA samples.

 

Deliverables

All customers receive their raw data as FASTQ files. Peak enrichment analysis and customizable data analysis packages are available by request.

NGS Platforms

GENEWIZ is a certified service provider for Illumina and Life Technology NGS platforms. For information on our NGS platforms as well as recommended configurations for your projects, please visit the NGS Platforms page. GENEWIZ does not guarantee data output or quality for sequencing only projects.



How To Order


Email | Phone (1-877-GENEWIZ (436-3949), Ext. 1) | Live Chat