Mutations are genetic alterations that are acquired either in germ or non-germ (somatic) cells. They can contribute to various diseases and may affect the response of a patient to particular drug treatments. The mutation can be an insertion, deletion, missense or nonsense mutation in the coding or non-coding regions. In some cases, a mutation occurs at the intron-exon boundary and affects the normal splicing of the transcript.
Sanger-based mutation analysis, mutation screening, exon resequencing, and SNP discovery all involve high volumes of PCR amplification and sequencing. Whether you are using Sanger as your primary approach for SNP screening and mutation detection, or as a confirmation of NGS or microarray results, GENEWIZ can help expedite your SNP and mutation analysis assays. Utilize GENEWIZ's extensive expertise to support your SNP and mutation analysis research objectives with speed, quality, and reliability.
Mutation Analysis Turnaround Time Comparison: GENEWIZ versus In-house